Research: functional consequences of metabolic and nutritional disturbances at rest and in exercise in health, diabetes, obesity and cardiovascular disease. Studies involve catecholamine measurement and assessment of sympathetic nervous activity; blood and tissue sampling for hormone levels, substrate turnover and oxidation; assessing cardiovascular and cognitive responses.

Interests

• Human metabolism and dietary alterations in health and disease.
• Fat, carbohydrate and energy metabolism, in exercise, over- and under-nutrition.
• Metabolic disturbances in obesity and diabetes.
• Metabolic and nutritional factors affecting cognitive function.
• Effects of nutrients on vascular function

Techniques

• Energy expenditure and body composition.
• Hormone and metabolite assays in blood.
• Metabolites and gene expression in biopsies of adipose tissue and skeletal muscle.
• Measurement of whole body sensitivity to insulin, to catecholamines, and responses to single meals and dietary manipulation.
• Non-invasive assessment of cardiovascular function.

Projects

• Dietary and lifestyle factors affecting diabetes risk (EU FP7)
• Metabolic and appetite effects of bedrest and hypoxia (EU FP7).
• The effects of food products on appetite, satiety and food intake (Food industry).
• Impact of Diet and Exercise on NAFLD and insulin sensitivity (NIHR)
• Effects of food ingredients on nutrient bioavailability (Food industry)
• Psychosis and the role of inflammation and GABA/ Glutamate (Research Council)

MSc Integrated Physiology in Health and Disease;

http://www.nottingham.ac.uk/pgstudy/courses/biomedical-sciences/integrated-physiology-in-health-and-disease-msc.aspx

MSc Sports Medicine;
http://www.nottingham.ac.uk/pgstudy/courses/medicine/medical-sciences/sports-and-exercise-medicine-msc.aspx